Microbiota and the brain-gut connection
Written by Stefanie Twist
Reviewed by Dr. Premsyl Bercik
In the past few years, attention devoted to microbiota and the brain-gut connection has increased. Gut microbiota encompasses the bacterial colonies, fungi, viruses, and other microbes that live within our gastrointestinal tract.(1, 2) Importance of bacteria in our GI tract should not be understated as they contribute to key biological processes in our body. However, when there are changes to this balance, it can be the reason symptoms develop.
Microbiota development starts at birth. Factors such as vaginal versus cesarean birth and breastfeeding versus formula shape the diversity and proliferation of strains of bacteria.(2, 3) Human breastmilk has nutrients which can help shape the microbiome and immune development of children. Infant’s initial exposure to microbiota is through the act of birth. Cesarean section births correlated with increased risk of children developing celiac disease, asthma, type 1 diabetes, and obesity.(4) This may occur because infants born vaginally are exposed to their mother’s vaginal microbiota while those born via cesarean are not.
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A Message from the ANMS President John Pandolfino, MD
It is both a privilege and honor for me to assume the role of President of the American Neurogastroenterology and Motility Society and to continue to work with an exceptional group of staff, councilors and officers. This is an unprecedented time in our history for both our society and our global community as we deal with a world-wide pandemic, and begin to truly address many of the inequities that have plagued society and our academic culture. I am humbled by this opportunity, and believe the ANMS can make a substantial contribution by addressing these issues head-on, and evolving into a new academic society focused on collaboration and developing deep ties to our community.
I have been involved with the ANMS since I was a trainee, and have been in a continuous leadership role since 2012 when I was elected to council, and subsequently became treasurer and president-elect. Over this time, I was fortunate to work with multiple presidents, such as Drs. Beverley Greenwood-Van Meerveld, Gianrico Farrugia, John Wiley, and Lin Chang. Happily, I will be able to continue to work with Drs. Beverley Geenwood-Van Meerveld and John Wiley, as they help solidify the future of the ANMS with their leadership roles in the ANMS Institute. Dr. Greenwood-Van Meerveld will take over as Director of the Institute, and Dr. John Wiley will remain as an advisor to the Institute, to maintain a strong continuity with our industry partners.
Over the last four years, we have also had an amazing team of ANMS councilors, and we are always sad to see exceptional people rotate off council. I would personally like to thank Drs. Miranda van Tilburg, William Chey, Elyanne Ratcliffe, and Purna Kashyap for their amazing contributions to the ANMS. These councilors have helped our society develop an amazing social media presence, an exceptional grant process to fund young investigators, and an excellent series of cutting-edge educational programs. These projects have showcased the important role ANMS has taken in educating and training our members and the next generation of leaders. This great work will continue with our remaining councilors: Drs. Jose-Garza, Simon Gibbons, Baharak Moshiree, and Linda Nguyen, and our newly elected councilors: Drs. Jason Baker, Katja Kovacic, David Levinthal, Eamonn Quigley, Shanthi Srinivasan, and Gregory Sayuk. I would also like to congratulate Dr. Nicholas Verne for his election as the new President-Elect and Dr. Fedias Christofi, who will assume the role of Treasurer. Last, Dr. C. Prakash Gyawali will transition from his role as councilor and continue his work as an ex-officio member focusing on our Clinical Training Program and curriculum development with our global sister societies. I look forward to working with them over the next two years in my role as president.
2021 ANMS Annual Meeting
Clinical Course: Providing the best clinical care for our patients
Scientific Meeting: Advancing patient care through cutting edge research
Young Investigator Forum: Developing our future researchers in Neurogastroenterology and Motility. The top 15 abstracts will be chosen to participate in this one-on-one mentoring program over 1.5 days
Date: August 13-15, 2021
Location: Westin Boston Waterfront, Boston Massachusetts
Abstract Deadline: March 26, 2021 (by midnight EST)
View program here.
Registration and Abstract Submission portal will open mid-February.
2021 ANMS Virtual Symposia Schedule for both Clinical and Basic Science
Clinical Symposia Theme: Better Together: Bridging the Divide Between Pediatrics and Adult GI Motility Disorders
Basic Science Symposia Theme: Basic Concepts in Neurogastroenterology
Visceral Pain: The endocannabinoid system and visceral pain: Its relevance to irritable bowel syndrome
Sponsored by Arena Pharmaceuticals, Inc.
February 24, 2021 –3 pm PT/5 pm CT/6 pm ET
Moderator: John Wiley
RESCHEDULED to 2021
FNM 2020 – 4th Meeting of the Federation of Neurogastroenterology and Motility and Postgraduate Course on Gastrointestinal Motility
Hosted by: Australasian of Neurogastroenterology and Motility Association, Inc
Date: April 14-17, 2021
Location: Adelaide, Australia
CANCELLED: XVIth Little Brain Big Brain meeting (LBBB)
Date: March 22-25, 2020
Location: Port Elliot YHA, South Australia
The Mission and Goals of the ANMS
The American Neurogastroenterology and Motility Society is an organization that was established in 1980 dedicated to the study of neurogastroenterology and gastrointestinal motility and functional GI disorders.
Mission of the ANMS
To be the multidisciplinary society leading the field of neurogastroenterology by fostering excellence in research, education, training, and patient care.
Neurogastroenterology encompasses the study of brain, gut, and their interactions with relevance to the understanding and management of GI motility and functional GI disorders.
ANMS Condemns Racism, Injustice and Inequality
The ANMS condemns any cases of racism, injustice and inequality in America. As a scientific and medical society, the ANMS leadership would like to emphasize the importance of fostering diversity, equity and inclusion. We must dedicate ourselves to removing barriers that exclude persons of color from participation in our community. As a multidisciplinary society leading the field of neurogastroenterology and motility we must foster collaborations and support each other during these challenging times.
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ANMS Discovery Grants Program
ANMS will be offering up to 3 grants – Deadline: April 1, 2021
ANMS is accepting grant applications as part of the ANMS Discovery Grants Program. We will provide support for senior GI fellows, postdoctoral research fellows, or Instructor/Assistant Professor-level faculty who are pursuing research careers in the area of neurogastroenterology and GI motility. Up to three grants of up to $30,000 each will be awarded in 2021 for qualified applicants including senior GI fellows, postdoctoral research fellows, or junior faculty (with no prior or current independent grant funding, i.e. PI status on an R level grant) pursuing projects spanning basic science, translational investigation, and clinical research pertaining to neurogastroenterology and GI motility.
Applicants must be members of the ANMS at the time of application and also the mentors must be ANMS members. The application deadline is April 1, 2021. Applicants will be notified on the outcome of their application by July 1, 2021 and the award period will begin September 2021. Click here for more information and to submit your on-line application.
Objective: To assist promising trainee and junior faculty investigators in carrying out research projects in the area of neurogastroenterology and motility. The ANMS welcomes applications related to a broad range of topics and research methodologies that are relevant to this field. These grants are intended to support investigators generate sufficient preliminary data to obtain extramurally-funded research grants and to promote career development in the area of neurogastroenterology and motility.
Description: The ANMS Discovery Grants will provide support for senior GI fellows, postdoctoral research fellows, or Instructor/Assistant Professor-level faculty who are pursuing research careers in the area of neurogastroenterology and GI motility. Up to three grants of up to $30,000 each will be awarded in 2021 for qualified applicants including senior GI fellows, postdoctoral research fellows, or junior faculty (with no prior or current independent grant funding, i.e. PI status on an R level grant) pursuing projects spanning basic science, translational investigation, and clinical research pertaining to neurogastroenterology and GI motility. Grant applications should clearly describe how investigators intend to use the pilot data for future studies, how the work will enhance applications for extramural research funding, and where the work fits within their overall career goals.
Eligibility: Applicants must be a GI fellow trainee, post-doctoral research fellow, or a faculty member at the Instructor or Assistant Professor level with a primary appointment at an academic institution. Applicants must also be a member or trainee member of the ANMS at the time of application, and mentors must also be an ANMS member. Information on becoming a member of the ANMS can be found at www.motilitysociety.org. It is anticipated that successful candidates will maintain their membership with the ANMS.
Applications will be evaluated by members of the Research Committee.
The American Neurogastroenterology and Motility Society (ANMS) Research Committee is launching a Mentoring Program in Neurogastroenterology and Motility to help young clinicians and scientists (MDs, PhDs, or DVMs) as they start their research career in the areas of neurogastroenterology and gastrointestinal motility. The areas of interest can be varied and the research may take the form of clinical investigation, basic science research, or translational science research. The objective of the program is to provide guidance to individuals at an early stage of their career who may enter the field of neurogastroenterology and gastrointestinal motility.
Manuscripts Sponsored by ANMS on Clinical Topics in GI Motility
Training in gastrointestinal motility.
Dig Dis. 2006;24(3-4):221-7.
Murray JA, Clouse RE, Conklin JL.
Components of the standard esophageal manometry.
Neurogastroenterology and Motility 2003;15(6):591-606.
Gastroesophageal Reflux Disease.
N Engl J Med 2008;359:1700-7.